The copper peptide GHK Cu is a naturally occurring tripeptide composed of the amino acids glycine, histidine, and lysine, with a copper ion attached to it.
It is naturally found in human plasma, serum, and saliva and is currently being incorporated in hair and cosmetic products for its regenerative and protective properties.
GHK-Cu’s mechanism of action is not fully understood and is still being studied in research. However, through laboratory research and clinical trials, GHK-Cu appears to promote the synthesis of new collagen and elastin fibers within the dermis. GHK-Cu may help strengthen the skin matrix and improve firmness and elasticity by stimulating skin cells called fibroblasts.
GHK-Cu also displays the ability to work as a synthetic antioxidant. Studies show it neutralizes free radicals that increase the speed of skin aging.
Research has demonstrated that GHK copper peptide promotes hair growth by enhancing hair follicle health and activating pathways that stimulate hair growth. Above all, GHK-Cu is being studied for its anti-inflammatory effects that may affect:
While more research is still needed, these regenerative, antioxidant, and anti-inflammatory mechanisms likely play a key role in allowing GHK-Cu peptides to improve skin tightness, smoothness, and vibrancy when applied topically.
GHK-Cu is a naturally occurring peptide found in urine, serum, and saliva. Copper peptides are unique as they each have one or more copper ions attached to them to enhance their properties.
These peptides are being studied to promote skin healing and regeneration by stimulating collagen synthesis, enhancing skin health, and reducing rough skin appearance. Additionally, they have shown analgesic effects and potential benefits for nerve outgrowth and nervous system function in recent research.
The reported benefits of GHK copper peptide in recent research include skin healing and regeneration, increased hair growth, and potential anti-aging properties due to its role in stimulating collagen synthesis, extracellular matrix components, and reducing inflammatory molecules.
Yes, GHK copper peptide has been shown to increase hair growth in clinical studies by promoting hair follicle health and stimulating hair growth pathways.
GHK copper peptide is generally well-tolerated with minimal side effects reported. However, individuals with compromised immune systems or specific medical conditions should exercise caution and consult with a healthcare professional before signing up for laboratory research with copper peptides as these are research chemicals for research use only.
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1. Bissett, D. L. (2005). Anti-aging skin care formulations. In Cosmetic formulation of skin care products (pp. 191-210). CRC Press.
2. Pickart, L., Vasquez-Soltero, J. M., & Margolina, A. (2015). GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration. BioMed research international, 2015.
3. Pickart, L., & Margolina, A. (2018). Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene data. International journal of molecular sciences, 19(7), 1987.
4. Pickart, L. (2008). The human tri-peptide GHK and tissue remodeling. Journal of Biomaterials Science, Polymer Edition, 19(8), 969-988.
5. Dou, Y., Lee, A., Zhu, L., Morton, J., & Ladiges, W. (2020). The potential of GHK as an anti-aging peptide. Aging pathobiology and therapeutics, 2(1), 58.
6. Anastassakis, K. (2022). Copper Tripeptides Copper tripeptides. In Androgenetic Alopecia From A to Z: Vol. 2 Drugs, Herbs, Nutrition and Supplements (pp. 225-230). Cham: Springer International Publishing.
7. Wang, X., Liu, B., Xu, Q., Sun, H., Shi, M., Wang, D., … & Feng, B. (2017). GHK‐Cu‐liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis. Wound repair and regeneration, 25(2), 270-278.
8. Zhao, R., Chen, Y., Ma, Y., Zou, C., Zhang, J., & Chen, Z. (2022). Innovation and transformation of chronic airway diseases. Frontiers in Molecular Biosciences, 9, 1089813.
9. Lau, S. J., & Sarkar, B. (1981). The interaction of copper (II) and glycyl-L-histidyl-L-lysine, a growth-modulating tripeptide from plasma. Biochemical Journal, 199(3), 649-656.
10. Pickart L, et al. The human tri-peptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging: implications for cognitive health. Oxidative Medicine and Cellular Longevity. 2012; 2012: 324832. doi: 10.1155/2012/324832.
Please note that the above references provide evidence for the potential benefits of GHK-cu Peptide as stated in the product description. For more in-depth information, kindly refer to these scholarly works.
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