At the forefront of groundbreaking research peptides offered by Research Chemical is MOTS-c—a peptide formulated from mitochondrial-encoded genes. MOTS-c stands out for its remarkable potential to regulate metabolism, captivating the interest of researchers across diverse fields.
Comprising a chain of 16 amino acids, MOTS-c has garnered prominence for its role in research studies for modulating metabolism and shaping cellular energy production. This characteristic positions MOTS-c as a pivotal molecule in the investigation of metabolic disorders and associated conditions.
Its ability to influence the energetic dynamics within cells holds promise for critical research needed in metabolic pathway studies, paving the way for innovative approaches to addressing metabolic challenges.
The research on MOTS-c suggests various insight including:
1. Metabolic Regulation: Research suggests that MOTS-c plays a vital role in metabolic regulation by enhancing insulin sensitivity, improving glucose uptake, and boosting mitochondrial function, all contributing to achieving metabolic homeostasis.
2. Anti-Aging Effects: Investigations have shown the potential of MOTS-c as an anti-aging peptide, owing to its capacity to ameliorate age-related metabolic decline and bolster cellular health. MOTS-c is being studied for its capability to impact cellular metabolism and augment energy production, offering a pathway to heightened vitality and potential anti-aging benefits.
3. Cardiovascular Disease and Health:
This intriguing peptide has demonstrated a capacity to mitigate oxidative stress, enhance endothelial function, and regulate lipid metabolism in recent research.
4. Neuroprotection:
Early-stage research suggests that MOTS-c may play a role in safeguarding neuronal health. Its ability to enhance mitochondrial function presents a compelling prospect for countering neurodegenerative conditions. Additionally, the demonstrated capacity to reduce oxidative stress further amplifies its potential in the area of neuroprotection. Continued research endeavors are essential to reveal the precise mechanisms underlying these neuroprotective qualities, providing a solid foundation for potential therapeutic interventions aimed at neurodegenerative disorders.
As an investigational peptide with potential therapeutic implications, MOTS-c presents a compelling avenue for understanding and potentially addressing cardiovascular health. Its ability to reduce oxidative stress and positively influence endothelial function holds promise for the development of innovative strategies in cardiovascular disease management. Moreover, its modulation of lipid metabolism adds another layer of interest, hinting at a multifaceted approach to cardiovascular well-being through the lens of MOTS-c. Further research in this domain is crucial for the full scope of its cardiovascular findings.
The mitochondrial encoded peptide MOTS-c was tested to regulate nuclear gene expression, improve diet-induced insulin resistance, and enhance cellular energy levels in recent studies. It has shown potential benefits in addressing age-dependent insulin resistance, endothelial cell dysfunction, and metabolic stress.
MOTS-c peptide and other mitochondrial-derived peptides play a crucial role in enhancing mitochondrial communication, protecting lean body mass, and improving mitochondrial function as seen in animal studies. It has been studied for its potential benefits in addressing hepatic mitochondrial dysfunction and age-related insulin resistance. These studies are still ongoing.
MOTS-c plays a significant role in research related to energy regulation and enhancing cellular energy levels. It is being studied for how it influences glucose transporters, enhances insulin sensitivity, and promotes mitochondrial function, all contributing to improved energy metabolism and exercise capacity.
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1. Lee C, Zeng J, Drew BG, et al. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metabolism. 2015 Apr 7;21(3):443-54. doi: 10.1016/j.cmet.2015.02.009.
2. Wan, W., Zhang, L., Lin, Y., Rao, X., Wang, X., Hua, F., & Ying, J. (2023). Mitochondria-derived peptide MOTS-c: Effects and mechanisms related to stress, metabolism and aging. Journal of Translational Medicine, 21(1), 1-13.
3. Gao, Y., Wei, X., Wei, P., Lu, H., Zhong, L., Tan, J., … & Liu, Z. (2023). MOTS-c Functionally Prevents Metabolic Disorders. Metabolites, 13(1), 125.
4. O’neill, H. M. (2013). AMPK and exercise: glucose uptake and insulin sensitivity. Diabetes & metabolism journal, 37(1), 1-21.
5. Lee, C., Kim, K. H., & Cohen, P. (2016). MOTS-c: a novel mitochondrial-derived peptide regulating muscle and fat metabolism. Free Radical Biology and Medicine, 100, 182-187.
6. Lu, H., Wei, M., Zhai, Y., Li, Q., Ye, Z., Wang, L., … & Lu, Z. (2019). MOTS-c peptide regulates adipose homeostasis to prevent ovariectomy-induced metabolic dysfunction. Journal of Molecular Medicine, 97, 473-485.
7. Priest, C., & Tontonoz, P. (2019). Inter-organ cross-talk in metabolic syndrome. Nature Metabolism, 1(12), 1177-1188.
8. Ruzankina, Y., Schoppy, D. W., Asare, A., Clark, C. E., Vonderheide, R. H., & Brown, E. J. (2009). Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53. Nature genetics, 41(10), 1144-1149.
9. Ahn, C. H., Choi, E. H., Kong, B. S., & Cho, Y. M. (2020). Effects of MOTS-c on the mitochondrial function of cells harboring 3243 A to G mutant mitochondrial DNA. Molecular biology reports, 47, 4029-4035.
Please note that the above references provide evidence for the potential benefits of MOTS-c Peptide as stated in the product description. For more in-depth information, kindly refer to these scholarly works.
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